Abstract:MicroRNA (miRNA) is a kind of naturally occurring short noncoding small molecular RNA, which regulates gene expression at the posttranscriptional level through its sequence complementation with target mRNAs. Researches have shown that different malignant tumors, including diffuse large B cell lymphoma, have specific miRNA expression profiles. Therefore, miRNAs expression level of specimens of body fluids and tissues is expected to be the new indicator for assessing diffuse large B cell lymphoma.

Key words:MicroRNAs,Lymphoma,large Bcell,diffuse