Journal of International Oncology››2014,Vol. 41››Issue (8): 588-592.doi:10.3760/cma.j.issn.1673-422X.2014.08.010

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Prevention and therapy of small cell lung cancer with brain metastasis

Gao Chao, Yu Yonghua

  1. School of Medicine and Life Sciences, University of Ji′nanShandong Academy of Medical Sciences; Second Department of Radiation Oncology, Shandong Cancer Hospital, Ji′nan 250062, China
  • Received:2014-02-24Revised:2014-03-26Online:2014-08-15Published:2014-08-14
  • Contact:Yu Yonghua E-mail:sdyonghuayu@163.com

Abstract:Small cell lung cancer with brain metastasis is the most common type in brain metastasis tumors with the poor prognosis. Researches show that prophylactic cranial irradiation is not only effective in the prevention and treatment of limited disease brain metastases of small cell lung cancer, but also effective for extensive disease. Moreover, certain medications such as mannitol, nimustine etc also play an important supporting role, but there are many other uncertain parts in terms of prevention and treatment remaining controversial and needing further research.

Key words:Carcinoma, small cell,Lung neoplasms,Neoplasm metastasis,Radiotherapy,Drug therapy

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