姓名：张春雨
硕士生导师
职称：副教授
联系方式：zhangchunyu@sdfmu.edu.cn
研究方向：
1.铂类抗肿瘤药物开发及治疗应用;
2.基于金属团簇药物/探针的纳米生物效应研究;
3.基于先进光源的单细胞同步辐射成像分析。
主要学术任职：
1.担任Nano Today, Biomaterials, Journal of Controlled Release等期刊审稿人
主持科研课题：
1.中国博士后科学基金,面上项目, 2022M711974, 2022/06-2023/09, 8万元,已结题,主持;
2.百度开云体育app青年科学基金培育资助计划项目, 202201-003, 2022/10-2024/10, 10万元,已结题,主持;
3.山东省医药卫生科技项目,青年项目, 202313030397, 2024/01-2025/12, 2万元,在研,主持;
4.百度开云体育app高层次人才引进经费资助项目, 2023/09-2028/08, 100万,在研,主持。
近五年代表性论文（限第一作者和通讯作者）：
(1) Chao Xu, Juanjuan Guo, Qinqin Zheng, Mingchuan Yang, Zhenduo Han, Na Zhang,ChunyuZhang,*Hongping Chen* and Xiangchun Zhang,* Personalized design enzyme-like activity theanine coated Pt clusters for catalytic damage of bacterial and infection management.Chemical Engineering Journal2025,505, 159309.
(2)Chao Xu, Dongfang Xia, Xiangchun Zhang, Qingqiang Yao, Yaling Wang,*Chunyu Zhang,*In situ analysis of metallodrugs at the single-cell level based on synchrotron radiation technology.TrAC-Trends in Analytical Chemistry2024,171, 117515.
(3)Chunyu Zhang,*Na Zhang, Wenchao Niu, Ruihan Li, Yanna Liu, Yanling Mu, Chao Xu,* Qingqiang Yao,* Xueyun Gao,*Ultrasmall platinum nanoclusters: A potent chemotherapeutic drug for cancer-specific DNA damage with optimizing therapeutic efficacy while minimizing systemic toxicity.Nano Today2024,55, 102195.
(4)ChunyuZhang,#KaiZhang,#YanyanCui,#YuecongGuo, ChuanWang, ChaoXu, QingqiangYao,YuliangZhao, ChunyingChen,* YalingWang,*Multifunctional Nanoprobe for 3D Nanoresolution Imaging of Intact Cell HER2 Protein with Hard X-ray Tomography.Anal.Chem.2023,95,2129-2133.(Cover article)
(5)ChunyuZhang,#ChaoXu,#XueyunGao,*QingqiangYao,*Platinum-based Drugs for Cancer Therapy and Anti-tumor Strategies.Theranostics2022,12, 2115-2132. (Highly Cited Paper)
(6)Zhesheng He,#Fei Ye,#Chunyu Zhang,#Jiadong Fan,#Zhongying Du, Wencong Zhao, Qing Yuan, Wenchao Niu, Fuping Gao, Bo He, Peng Cao, Lina Zhao, Xuejiao Gao, Xingfa Gao, Bo Sun, Yuhui Dong, Jincun Zhao, Jianxun Qi, Xing-Jie Liang, Huaidong Jiang,*Yong Gong,*Wenjie Tan,*Xueyun Gao,*A Comparison of Remdesivir Versus Gold Cluster in COVID-19 Animal Model: A Better Therapeutic Outcome of Gold Cluster.Nano Today2022,44, 101468.(co-first author）
(7)ChunyuZhang,ShengkunYao, ChaoXu, YananChang, YunbingZong, KaiZhang, XiangzhiZhang, LijuanZhang, ChunyingChen, YuliangZhao, HuaidongJiang,*XueyunGao,*YalingWang,*3D Imaging and Quantification of the Integrin at a Single-Cell Base on a Multisignal Nanoprobe and Synchrotron Radiation Soft X-ray Tomography Microscopy.Anal.Chem.2021,93, 1237-1241.
(8)ChunyuZhang,LiangGao,*QingYuan, LinaZhao, WenchaoNiu, PengjuCai, JiaojiaoLi, XuHan, ZheshengHe, FupingGao, YalingWang, HuaidongJiang, ZhifangChai, XueyunGao,*Is GSH Chelated Pt Molecule Inactive in Anti-Cancer Treatment? A Case Study of Pt6GS4.Small2020,16, 2002044.
