%A ZHANG Yong-Qu, DOU Xiao-Wei, ZHANG Guo-Jun %T Molecular targeted therapy for breast cancer patients based on Notch signal transduction pathway %0 Journal Article %D 2013 %J Journal of International Oncology %R %P 678-680 %V 40 %N 8 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9174.shtml} %8 2013-09-08 %X Studied show that the Notch signal transduction pathway involves in
theregulation and control of cell proliferation, differentiation and apoptosis. Aberrant Notch signaling can induce breast cancer in transgenic mice. High expressions of either Notch receptors or their ligands have been linked to poor prognosis in patients with
breast cancer. Inhibition of Notch signal transduction pathway may
be beneficial forbreast cancer treatment.