%A ZHOU Jian, TAO Lei %T Effect of IL-10 in tumor %0 Journal Article %D 2013 %J Journal of International Oncology %R %P 181-183 %V 40 %N 3 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9013.shtml} %8 2013-03-08 %X Interleukin-10 (IL-10) is an immuno-regulatory cytokine, which
is well knownfor its immunosuppressive function. IL-10 can act on a variety of immune cell subsets and play an immunosuppressive effect through a variety of ways. It plays an important role in the tumor immune escape. Recent studies show that IL-10 also has an immune-stimulating function, which is presumably a pluripotent cytokine. This paper will combine the latest literature to summary the positive and negative regulatory roles of IL-10, mediation ways in the tumor and the relationships with prognosis.