%A Yu Jishang, Wu Fan %T Advances of stanniocalcin 2 in tumors %0 Journal Article %D 2018 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2018.10.008 %P 615-618 %V 45 %N 10 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10529.shtml} %8 2018-10-08 %X Stanniocalcin 2, a secreted glycoprotein hormone, has been found to be highly expressed in a variety of human malignancies. Through several signal transdution pathways, stanniocalcin 2 plays important roles in the regulation of many biological events of tumor such as proliferation, apoptosis, invasion and metastasis, hypoxia tolerating and drug resistance, indicating stanniocalcin 2 may be a pivotal node in the molecular regulation network of tumor. Stanniocalcin 2 is expected to become a novel biomarker and therapeutic target for diagnosis and treatment of tumor if the funtional mechanisms of stanniocalcin 2 could be further elaborated.