%A Liu Weishuai, Zeng Yaqi, Shao Yuejuan, Wang Kun %T Dietary fiber intake and risk of prostate cancer: a Metaanalysis %0 Journal Article %D 2016 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2016.10.009 %P 758-764 %V 43 %N 10 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10065.shtml} %8 2016-10-08 %X ObjectiveTo determine the relationship between dietary fiber intake and risk of prostate cancer. MethodsElectronic databases including PubMed, EMBase, Cochrane library, China National Knowledge Internet (CNKI), Wanfang and CBM were searched to find eligible studies. Randomeffects relative risk (RR) and its corresponding 95%CI were used. Besides, randomeffects doseresponse analyses were also performed to clarify the doseresponse relations. ResultsTen studies, including five cohort studies and five casecontrol studies, were eligible and included in this Metaanalysis. The pooled RR of prostate cancer for the highest compared with the lowest dietary fiber intake was 0.87 (95%CI: 0.770.99, Z=2.10, P=0.035). In addition, pooled estimated data showed that risk of prostate cancer was significantly associated with soluble fiber (RR=0.78, 95%CI: 0.640.95, Z=2.45, P=0.014) and insoluble fiber (RR=0.65, 95%CI: 0.450.88, Z=2.79, P=0.005), but not with fruit, vegetable and cereal fiber intake. However, in doseresponse analysis, no significant association was reported （RR=0.996， 95%CI： 0.9891.002）. Sensitivity analysis showed that the overall results were relatively stable, and omission of any single study had little effect on the combined results. ConclusionDietary fiber intake is negative related to the risk of prostate cancer. Intake of dietary fiber is recommended to prevent prostate cancer. Considering the limitations of the included studies, more welldesigned prospective studies will be needed to confirm our findings.