Journal of International Oncology››2014,Vol. 41››Issue (10): 734-736.doi:10.3760/cma.j.issn.1673422X.2014.10.005

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LASS family and tumor

XIONG Tao, WANG Hai-Feng, WANG Jian-Song

  1. Department of Urology, Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China
  • Online:2014-10-29Published:2014-10-11
  • Contact:WangJiansong E-mail:jiansongwang@yahoo.com

Abstract:LASS gene family is a group of highly conserved and longevous gene LASS protein has a ceramide synthase activity, which can synthesize different types of ceramides. Ceramide is a key intermediate in tumor cells growth, signal transduction and other aspects. Thus it is inferred that the expression of LASS gene can suppress the occurrence and development of tumor within a certain range.

Key words:Ceramides,Genes, tumor suppressor,Neoplastic process

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